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Protein Facility Lead Scientist - 38 hours p/w

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We are looking for an experienced biochemist to run the Protein Facility within the Hubrecht Institute. The Protein Facility was launched in 2021 to support Hubrecht research groups with a variety of protein-related projects including protein purification, characterization and biochemical assay development. The successful candidate will work within the laboratories of Prof. and Dr. Francesca Mattiroli, with access to state-of-the-art biochemical equipment and expertise. Initial onboarding will be done with expert personnel. An important aspect of the position is the clear and goal-oriented communication with scientists from diverse research areas within the Institute.

The successful candidate will express and purify proteins from different systems (bacteria, yeast and insect cells), perform quality control procedures and protein characterization, design new tools based on the users' needs (e.g. set up new protocols, devise new analyses strategies), and advice and/or teach users. Critical skills involve the systematic documentation of the lab procedures, proper planning, and independence. An enthusiastic and constructive work attitude, with good communication skills is a prerequisite.

The position is open to candidates with MSc or HBO degrees. However, candidates with a PhD are strongly encouraged to apply, due to the ambitious and challenging nature of the projects. Established experience in biochemistry is required.

About the Hubrecht Institute

The Hubrecht Institute is a research institute focusing on developmental and stem cell biology. At the institute, more than 20 research groups perform fundamental and multidisciplinary research, both in healthy systems and disease models. The Hubrecht Institute is a research institute of the Royal Netherlands Academy of and Sciences (KNAW) and is located on the Utrecht Science Park 'De Uithof'. Since 2008, the institute has been affiliated with the University Medical Center Utrecht, advancing the translation of research into clinical practice. The Hubrecht Institute has a partnership with the European Molecular Biology Laboratory (EMBL).

Terms of employment

Depending on education and experience the minimum salary is € 3.546 and the maximum salary is € 5.538 gross per month for a full-time appointment (scale 10 cao Nederlandse Universiteiten/KNAW). This is exclusive of 8% vacation allowance, 8.3% year-end bonus, travel allowance, internet allowance, home working allowance and pension accrual with ABP.

The KNAW offers its staff an excellent package of secondary benefits. A package that meets the different needs of employees depending on their stage of life, lifestyle or career ambitions. For example, by working an extra two hours a week, it is possible to increase the number of days off from 29 to 41 days a year (with full-time employment).

For a complete overview of the terms of employment, please refer to the web page: werken bij de KNAW .

Applying for a Certificate of Good Conduct can be part of the employment procedure.

Diversity & Inclusion

The KNAW considers a working environment in which everyone feels welcome and appreciated of great importance. A working environment in which attention is paid to individual quality and where development opportunities are paramount. Together we strive for an inclusive culture in which we embrace differences. We would therefore like to invite candidates who want to contribute to this through their background and experience. In the event of equal suitability, preference will be given to the candidate who thus enhances diversity within the Academy.

For questions please contact or

Research group

Knipscheer group

Start date

01/02/2026

Location

Utrecht Science Park

Period

Full time